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TCM Herbal Practice on Drug Abuse

Harvey Y. Zhu, D.TCM

July 1999

Abstract:

Traditional Chinese medicine has been used for detoxification in the past 4,000 years. During the Opium War (1840-1842), the TCM physicians invented herbal formulae to treat hundreds of thousand opium smokers and helped them abstain successfully. The herbal formulae were almost lost until the late 1970’s. When reports of drug abuse rose dramatically during the economic open policy in China, Chinese physician rediscovered these formulae and applied them in over a hundred different levels of detoxification centre and hospital in China. Dr. Harvey Y. Zhu has practiced Chinese medicine on drug abuse in China during the 1970’s, and had researched with his colleagues. He recently used his previous experience to treat drug addicts in both the United States and Canada. The herbal formulae introduced here have been such well documented that they not only treat specific drug abuse but also target different aspects of the individual disharmonies. Practitioner is recommended to use other healing strategies to work with and adapt the herbal formulae to meet the changing therapeutic needs of the patient.

Cocaine/Crack

In addition to anxiety, memory loss, weight loss, insomnia, paranoia, skins picking and ulceration, cocaine user has extreme drug craving.

TCM practice considers that liver yang excess due to yin deficiency in both the liver and kidney is the syndrome of cocaine users. Complications can be seen very often. Patient appears to possess excessive manifestations, but is actually suffering a severe deficiency. Red and dry tongue; thready, rapid and weak pulses are the clinical signs. Therefore, nourishing the yin and suppressing the yang is the principle of the herbal treatment. Treatment of liver and kidney is the priority. Heart, lung and spleen should be dealt with afterwards.

The prescription of herbal is suggested as follow:

Antelopis Cornu  - (Antelope Horn) - Ling Yang Jia

Haliotidis Concha - (Abalone Shell) - Shi Jue Ming

Scrophulariae Radix - (Scrophularia) - Xuan Shen

Asparagi Radix - (Shiny Asparagus) - Tian Men Dong

Ligustri Fructus - (Privet) - Nu Zhen Zi

Paeoniae Radix - (White Peony) - Bai Shao

Rehmanniae Radix  - (Rehmannia) - Sheng Di Huang

Citri Immaturi Pericarpiumont - (Blue Citrus Peel) -  Qing Pi

Corydalidis Tuber - (Corydalis) - Yan Hu Suo

Bambusae Concretio Silicea - (Tabasheer) - Tian Zhu Huang

Dioscoreae Bulbiferae Rhizoma - (Dioscorea) -Huang Yao Zi

While on herbal program, patient is advised to avoid pungent flavour and greasy food. Seafood is recommended. Clinical data shows that 81% of the subjects have overcome anxiety within one week while 58% of the subjects have the craving decreased.

If the patient has additional symptoms, such as

Severe insomnia, add:

Salviae Miltiorrhizae Radix - (Red Sage Root) - Dan Shen

Sparganii Rhizoma - (Bulrush) - San Leng

Cyperi Rhizoma - (Cyperus) - Xiang Fu Zi

Saussureae Radix - (Costus Root) - Mu Xiang

Angelicae Radix - (Angelica) - Dang Gui

Gardeniae Fructus - (Gardenia) - Shan Zhi Zi

Agitated depression is the major withdrawal symptom. Soothing the liver qi, clearing away heart fire and tranquilizing the mind can alleviate mental depression.

Herbs are prescribed as follows:

Bupleuri Radix - (Bupleurum) - Chai Hu

Cyperi Rhizoma - (Cyperus) - Xiang Fu Zi

Fossilia Ossis Mastodi - (Dragon Bone) - Long Gu

Ostreae Testa - (Oyster Shell) - Mu Li

Acori Graminei Rhizoma - Shi Chang Pu

Curcumae Tuber - (Turmeric) - Yu Jin

Rehmanniae Radix - (Rehmannia) - Sheng Di Huang

Coptidis Rhizoma - (Coptis) - Huang Lian

Lophatheri Herba - (Lophatherum) - Dan Zhu Ye

Cinnabaris - (Cinnabar) - Zhu Sha

Zizyphi Spinosi Semen - (Jujube Seed) - Suan Zao Ren

Paeoniae Radix - (White Peony) - Bai Shao

Consistent herbal program required from six months to a year.

Tobacco/Nicotine

There are three stages of the symptoms of tobacco users: In the first few days of abstaining, they may be irritated, act aggressively, and have difficulty sleeping. The real challenge comes later. The temptation to pick up the tobacco product again can be very strong and user may be depressed, or feel great anxiety. Any number of events and situations can trigger relapse regardless of stress or relaxation, unhappiness or pleasure. Practitioner should be aware of that patients could possibly gain weight over a period of time once they have successfully abstained (79% of subjects has been recorded in clinical statistics). It is uncertain whether an increased appetite or a changed metabolism or both cause this.

To assist the person abstain from tobacco, TCM practitioner would usually take a step-by-step procedure in which nourishing the heart and calming the mind go first, strengthening the spleen and replenishing qi come after. That is the way we could take care of an individual during the period of abstention. Herbs are prescribed as follows:

Codonopsitis Radix- Dang Shen

Rehmanniae Radix - (Rehmannia)- Sheng Di Huang

Atractylodis Rhizoma - (Atractylodes) - Bai Zhu

Poria - (Hoelen) - Fu Ling

Ophiopogonis Tuber - (Ophiopogon) - Mai Men Dong

Paeoniae Radix - (White Peony) - Bai Shao

Polygoni Multiflori Caulis - He Shou Wu Teng

Crataegi Fructus - (Hawthorn) - Shan Zha

Oryzae Fructus - (Germinated Rice) - Gu Ya

Tritici Fructus - (Germinated Wheat) - Mai Ya

The herbs would technically dig out the nicotine dependence (by supporting the body’s function, physiologically and psychologically); clear the craving (by tranquilizing the mind and relieving the anxiety).

Have the decoction two to three times a day until succeed.

Follow up with herbs to eliminate food stagnancy, regulate gallbladder. This formula can enhance metabolism, keeping body in shape:

Crataegi Fructus - (Hawthorn) - Shan Zha

Alismatis Rhizoma - (Alisma)- Ze Xie

Raphani Semen - (Radish) - Lai Fu Zi

Tritici Fructus - (Germinated Wheat) - Mai Ya

Massa Medicata Fermentata -(Medicinal Leaven) - Shen Qu

Prunellae Spica - (Prunella)- Xia Ku Cao

Pericarpium Citri Reticulatae - (Tangerine Peel)- Chen Pi

Pharbitidis Semenv - (Morning Glory) - Qian Niu Zi

Cassiae Torae Herba - Cao Jue Ming

Poria - (Hoelen) - Fu Ling

Adsuki Bean - Chi Xiao Dou

Pogostemi Herba - (Patchouli) - Huo Xiang

Camelliae Folium - (Tea) - Cha Ye

Alcohol

Common alcohol withdrawal syndrome involves "the shakes", sweating, nausea, anxiety, and the more severe and potentially fatal condition, known as delirium tremens.

In TCM, most cases of alcohol addicts appear chronic intoxicated (alcoholism), develop an internal production of damp heat, leading to a stagnation of the qi and the blood.

Detoxifying liver is the priority. The principle of the treatment is to soothe the liver and to normalize the function of the gallbladder. The patient should be advised to have a healthy diet that is without grease. Herbs are prescribed as follows:

Artemisiae Capillaris Herba - (Capillaris)- Yin Chen

Gardeniae Fructus - (Gardenia) - Shan Zhi Zi

Rhei Rhizoma - (Rhubarb) - Da Huang

Phellodendri Cortex - (Phellodendron) - Huang Po

Alismatis Rhizoma - (Alisma) - Ze Xie

Curcumae Tuber - (Turmeric) - Yu Jin

Bupleuri Radix - (Bupleurum) - Chai Hu

Glycyrrhizae Radix - (Licorice) - Gan Cao

Baphicacanthis Rhizoma Et Radix - (Dyer’s Woad Root) - Ban Lan Gen

Hyperici Herba - Tian Ji Huang

Salviae Miltiorrhizae Radix - (Red Sage Root) - Dan Shen

* One dose a day, three days in a row. Take the following herbs as follow-up to rejuvenate the liver for two to three weeks:

Angelicae Radix - (Angelica) - Dang Gui

Batatatis Rhizoma - (Chinese Yam) - Shan Yao

Astragali Radix - Astragalus) - Huang Qi

Alismatis Rhizoma - (Alisma) - Ze Xie

Amydae Carapax - (Turtle Shell) - Bie Jia

Ostreae Testa - (Oyster Shell) - Mu Li

Sargassum - (Seaweed) - Hai Zao

Bupleuri Radix - (Bupleurum)- Chai Hu

Scutellariae Radix - (Scute) - Huang Qin

Poria - (Hoelen)- Fu Ling

Artemisiae Capillaris Herba - (Capillaris) - Yin Chen

Oldenlandiae Herba - (Spreading Hedyotis) - Bai Hua She She Cao

Scutellariae Barbatae Herba - Ban Zhi Lian

Heroin/Other Opiates

Common symptoms of heroin users are: decreased heart rate, blood pressure & respiration rate; constricted pupils, slurred speech, sedation, nausea and loss of appetite.

We often find deficiency of liver and kidney yin on heroin users. Reddened tongue, thready and rapid pulses are the proven signs. In order to support the heroin users to detoxify, TCM would focus primarily on treating the severe disharmonies in both the digestive system and nerve system by reinforcing with herbal remedy. Herbs are prescribed as follows:

Panacis Quinquefolii Radix - (American Ginseng) - Xi Yang Shen

Coptidis Rhizoma - (Coptis) - Huang Lian

Bupleuri Radix - (Bupleurum) - Chai Hu

Atractylodis Rhizoma - (Atractylodes) - Bai Zhu

Astragali Radix - (Astragalus) - Huang Qi

Aquilariae Lignum - (Aloeswood) - Chen Xiang

Angelicae Radix - (Angelica) - Dang Gui

Glycyrrhizae Radix - (Licorice) - Gan Cao

Saussureae Radix -(Costus Root) - Mu Xiang

Phellodendri Cortex - (Phellodendron) - Huang Po

Pericarpium Citri Reticulatae - (Tangerine Peel) - Chen Pi

Cimicifugae Rhizoma -(Cimicifuge) - Sheng Ma

Gastrodiae Rhizoma - (Gastrodia) - Tian Ma

Fossilia Ossis Mastodi - (Dragon Bone) - Long Gu

Ostreae Testa - (Oyster Shell) - Mu Li

The herbs prescribed above can significantly build up the patient’s healing power, overcome the withdrawal discomforts. Patient must avoid eating any sour taste foods. Success rate is 48% for those who remain on the herbal program for 1 month, while 66% for those who remain on it for 3 months, and 86% for those who remain on it for 7 months.

If the patient has additional symptoms, such as

Watery eyes, yawning, add:

Plantaginis Semen - (Plantain Seed) - Che Qian Zi

Cuscutae Semen - (Dodder) - Tu Si Zi

Rehmanniae Radix - (Prepared Rehmannia) - Shu Di Huan

Running nose, add:

Asari Herba Cum Radice - (Asarum)- Xi Xin

Schizonepetae Herba - (Schizonepeta) - Jing Jie

Cinnamomi Ramulus - (Cinnamon Twigs) - Gui Zhi

Xanthii Fructus - (Cocklebur) - Cang Er Zi

Angelicae Dahuricae Radix - (Angelica) - Bai Zhi

Profuse sweating, add:

Astragali Radix - (Astragalus) - Huang Qi

Oryzae Radix - (Glutinous Rice Stalk) - Nuo Dao Gen

Tritici Fructus - (Wheat) - Fu Xiao Mai

Ostreae Testa - (Oyster Shell) - Mu Li

Heroin user has severe withdrawal symptoms which are muscle pain, joints pain, tearing, nasal discharge, nausea, vomiting, loss of appetite, depression, cold limbs, "gooseflesh", dilated pupils and, increased blood pressure and heart rate.

In terms of TCM, it is believed that a severe deficiency of heart and spleen, and a severe deficiency of qi and blood are the typical syndromes of a heroin user. A pale tongue and a pulse of thready, deficiency type are the clinical evidences. The treatment principle should be nourishing the heart and spleen, relieving mental strain and depression, dispelling wind and eliminating dampness. Herbs are recommended as follows:

Ginseng Radix - (Ginseng) - Ren Shen

Pericarpium Citri Reticulatae - (Tangerine Peel) - Chen Pi

Pinelliae Tuber - (Pinellia) - Ban Xia

Atractylodis Rhizoma - (Atractylodes) - Bai Zhu

Angelicae Dahuricae Radix - (Angelica) - Bai Zhi

Pycnostelmae Herba - (Paniculate Swallowwort) - Xu Chang Qing

Poria - (Hoelen) - Fu Ling

Polyporus - Zhu Ling

Fossilia Ossis Mastodi - (Dragon Bone) - Long Gu

Tritici Fructus - (Wheat) - Fu Xiao Mai

Zizyphi Fructus - (Jujube) - Da Zao

Glycyrrhizae Radix - (Licorice) - Gan Cao

One dosage a day, three days in a row, and add:

Polygoni Multiflori Radix - He Shou Wu

Angelicae Radix - (Angelica) - Dang Gui

One dose a day, take seven days. Remove the following ingredient from the above prescription:

Pycnostelmae Herba - (paniculate Swallowwort) - Xu Chang Qing

Then, advise the patient to continue taking the remedy until complete recovery.

PCP (Phencyclidine)

Impaired coordination, flushed skin, sweating, agitation, amnesia, decreased light and pain sensitivity are acute effects of PCP. Large doses would cause convulsion, coma and death.

In TCM practice, patients are often viewed as having the mind being disturbed, which is caused by the upward perversion of the wind phlegm. White sticky tongue coating and a rolling pulse are the signs of the retaining of phlegm. Therefore, nourishing the heart, easing the mind, dispelling the wind and dissolving the phlegm, are immediately required. Prescription of the herbs is as follow:

Imperatae Rhizoma - Bai Mao Gen

Bambusae Concretio Silicea - (Tabasheer) - Tian Zhu Huang

Fossilia Ossis Mastodi - (Dragon Bone) - Long Gu

Ostreae Testa - (Oyster Shell) - Mu Li

Ramulus Uncariae cum Uncis - Gou Teng

Magnetite - Ci Shi

Paeoniae Radix - (White Peony) - Bai Shao

Lonicerae Caulis Et Folium - (Honeysuckle Stem) - Ren Tong Teng

Poria with Hostwood - Fu Shen

Cinnabaris - (Cinnabar) - Zhu Sha

Acori Graminei Rhizoma- Shi Chang Pu

Follow up with promotion of qi and blood herbal programs that continue enhancing the body resistance. The following herbs are recommended:

Ginseng Radix - (Ginseng) - Ren Shen

Astragali Radix - (Astragalus) - Huang Qi

Codonopsitis Radix - Dang Shen

Atractylodis Rhizoma - (Atractylodes) - Bai Zhu

Poria - (Hoelen) - Fu Ling

Batatatis Rhizoma - (Chinese Yam) - Shan Yao

Glycyrrhizae Radix - (Licorice) - Gan Cao

Rehmanniae Radix - (Prepared Rehmannia) - Shu Di Huang

Angelicae Radix - (Angelica) - Dang Gui

Cnidii Rhizoma - (Cnidium) - Chuan Xiong

Paeoniae Radix - (White Peony) - Bai Shao

Salviae Miltiorrhizae Radix - (Red Sage Root) - Dan Shen

Cervi Cornu Parvum - (Deer Horn) - Lu Rong

Cinnamomi Cortex - (Cinnamon Bark - Rou Gui

Eucommiae Cortex - (Eucommia) - Du Zhong

Lycii Fructus - (Wolfberry) - Gou Qi Zi

Zizyphi Spinosi Semen - (Jujube Seed) - Suan Zao Ren

Polygalae Radix - (Polygala) - Yuan Zhi

Pericarpium Citri Reticulatae - (Tangerine Peel) - Chen Pi

Amomi Fructus - (Amomum) - Sha Ren

Marijuana

Marijuana smoker has a unique clinical sign: bloodshot eyes (red eyes). Other symptoms are chronic cough without lung infection, chest pain, panic attacks and irregular menstrual cycles for women, irritability, mood shifts, impaired concentration, memory lapses and fatigue.

Clinical statistics indicates that marijuana smokers appear mainly to have lung yin deficiency. They may have sticky sputum, dry cough, dry mouth and throat, afternoon fever, night sweating, heat sensations in the palms and soles, a red tongue with small amount of coating and a thready, rapid pulse. Therefore, supplementing qi, nourishing yin and restoring the vital function from collapse are the strategies applied in TCM. Recommended herbs are:

Ginseng Radix - (Ginseng) - Ren Shen

Ophiopogonis Tuber - (Ophiopogon) - Mai Men Dong

Schizandrae Fructus - (Schizandra) - Wu Wei Zi

Fossilia Ossis Mastodi - (Dragon Bone) - Long Gu

Ostreae Testa - (Oyster Shell) - Mu Li

Corni Fructus - (Dogwood Fruit) - Shan Zhu Yu

Magnetite - Ci Shi

Achyranthis Radix - (Achyranthes) - Huai Niu Xi

Red eyes:

Scutellariae Radix - (Scute) - Huang Qin

Gardeniae Fructus - (Gardenia) - Shan Zhi Zi

One dose a day until succeeds.

LSD (Lysergic Acid Diethylamide)

Sensory distortion, dilated pupils, visual illusions, hallucinations, increased heart rate, slightly increase in blood pressure and temperature, gooseflesh, tremors, muscle twitching, nausea are the mostly seen acute effects.

TCM suggests clearing the hollow viscera and dissipating the toxin because the liver fire flares up and agitates the phlegm heat of Yangming. Yellow, sticky tongue coating, string-taut, rolling and rapid pulses can be seen in most cases. The prescription of herbs is:

Cinnamomi Ramulus - (Cinnamon Twigs) - Gui Zhi

Angelicae Radix - (Angelica) - Dang Gui

Glycyrrhizae Radix - (Licorice) - Gan Cao

Rhei Rhizoma - (Rhubarb) - Da Huang

Natrium Sulfuricum - (Mirabilitum) - Mang Xiao

Persicae Semen - (Peach Kernel) - Tao Ren

Paeoniae Radix - (White Peony) - Bai Shao

Moutan Radicis Cortex - (Moutan) - Mu Dan Pi

77% of 13 subjects start urine and bowl discharges in 5 hours while 23% of them have discharges in 10 hours. Repeat the herbal remedy accordingly. Follow up with herbs to nourish the kidney yin:

Rehmanniae Radix - (Rehmannia) - Sheng Di Huang

Scrophulariae Radix - (Scrophularia) - Xuan Shen

Lichi Fructus - (Wolfberry Fruit) - Gou Qi Zi

Ligustri Fructus - (Privet) - Nu Zhen Zi

Cuscutae Semen - (Dodder) - Tu Si Zi

Amydae Carapax - (Turtle Shell) - Bie Jia

Tortoise Plastron - Gui Ban

Haliotidis Concha - (Abalone Shell) - Shi Jue Ming

Pteriae Concha - (Mother of Pearl) - Zhen Zhu Mu

Zizyphi Spinosi Semen - (Jujube Seed - Suan Zao Ren

Thujae Orientalis Semen - (Biotae Semen) - Bai Zi Ren

Ophiopogonis Tuber - (Ophiopogon) - Mai Men Dong

Making decoction:

1. Place the herbs in a non-metal cooking pot, (e.g. clay pot, glass pot, pyrex, etc.) with cold water (1.5-2 litres of water, depending on the size of the pot). Soak it for half an hour or so.

2. Bring the water to boil and cover the pot tightly, then simmer it until it reduces to approximately 2 cups. Strain the decoction out and save it.

3. Re-cook the leftover herbs by adding another 1 litre of water and make 2 cups of decoction with the above-mentioned procedure.

4. Mix up the 4 cups of decoction together. This is a two-day supply.

5. Ready to serve. Keep decoction refrigerated.

6. 2 cups a day. Drink it warm.

Discussion:

1. Chinese herbal practice is base on the philosophy of traditional Chinese medicine. The characteristic is treating the person rather than treating the symptoms. While using the herbs on drug abuse, practitioners should study the constitution of the patient before administering herbal remedy to patient.

2. The amount of the herbs might not be conventional. It is necessary to be modified and varied base on the individual’s symptoms, complexity of drug involvement and, consumption of chemicals.

3. Using traditional Chinese herbs to treat drug addicts should not be a quick fix. Attempts to cut off, or to separate, from mainstream health care are medically wrong and can even be fatal.

4. Drug users always appear in unstable conditions. It is highly recommended that they should be provided with close attention. Respect the TCM rules: ongoing program; daily follow up; preventive, individual and holistic approach; as well as functional back up.

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